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Clinicopathologic Correlations of HIV-1-Associated Vacuolar Myelopathy:An Autopsy-Based Case-Control Study Neurol 44:2159-2164, DalPan,G.J.,et al, 1994 See this aricle in Pubmed Article Abstract To determine the clinical correlates of HIV-1-associated vacuolar myelopathy(VM)we designed a case control study based on 215 AIDS autopsies in which we examined the spinal cord.We defined a case as an individual dying with AIDS and with VM present at autopsy;we defined a control as an individual dying the AIDS without VM.VM was found in 100 of 215(46.5) autopsies,with no apparent temporal trends.VM is a common neuropathologic finding that is frequently unrecognized during life.The association with the number of systemic illnesses,M.avium-intracellulare infection and P. carinii pneumonia suggests that the development of VM is related to the severity of immunosuppression.

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(click to filter results - removes previous filter) acquired immunodeficiency syndrome acquired immunodeficiency syndrome myelopathy human immunodeficiency virus type 1 immunosuppression leg weakness,bilateral myelopathy myelopathy,vacuolar neuropathology opportunistic infection paraparesis paraparesis,spastic spinal cord,lesion of spinal cord,pathologic exam of

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